Barton-McCombie Deoxygenation

The Barton-McCombie deoxygenation, also known as the Barton-McCombie reaction, is a chemical reaction used in organic synthesis to selectively remove oxygen functional groups, such as alcohols or ethers, from organic molecules. The reaction was developed by Derek H. R. Barton and Stuart McCombie in the 1970s. The general reaction scheme for the Barton-McCombie deoxygenation is…